Grasping nettles

Grasping nettles: cellular heterogeneity and other confounders in epigenome-wide association studies

Platform technologies for measurement of CpG methylation at multiple loci across the genome have made ambitious epigenome-wide association studies affordable and practicable. In contrast to genetic studies, which estimate the effects of structural changes in DNA, and transcriptomic studies, which measure genomic outputs, epigenetic studies can access states of regulation of genome function in p...

Stinging nettles for osteoarthritis pain of the hip.

Extending fingertip grasping to whole body grasping

Grasping neurones

We agree with Robertson that our new view on grasping is a description of motor behaviour rather than offering any insight into the nature of the neural processing underlying this behaviour. However, neurophysiologists might be inspired by our new view to ask other questions, do other experiments, and analyse these differently. In this way, they could generate new insights about the neural cont...

Grasping Complexity

The century of complexity has come. Many people write and speak about complexity. The statement of the great physicist Stephen Hawking, “I think the next century will be the century of complexity,” in his ‘millennium’ interview on January 23, 2000 (San Jose Mercury News) became a widely cited prophecy. The face of science has changed (see cartoon in Fig. 1). Surprisingly, when we start asking a...